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Surface plasmon resonance based biosensor technique: A review

Identifieur interne : 002313 ( Main/Exploration ); précédent : 002312; suivant : 002314

Surface plasmon resonance based biosensor technique: A review

Auteurs : Xiaowei Guo [Corée du Sud, République populaire de Chine]

Source :

RBID : ISTEX:2CD2E5597F0E6F349BB8EF5417F503495B8B2AFA

English descriptors

Abstract

Optical Surface plasmon resonance (SPR) biosensors represent the most advanced and developed optical label‐free biosensor technology. Optical SPR biosensors are a powerful detection and analysis tool that has vast applications in environmental protection, biotechnology, medical diagnostics, drug screening, food safety and security. This article reviews the recent development of SPR biosensor techniques, including bulk SPR and localized SPR (LSPR) biosensors, for detecting interactions between an analyte of interest in solution and a biomolecular recognition. The concepts of bulk and localized SPs and the working principles of both sensing techniques are introduced. Major sensing advances on biorecognition elements, measurement formats, and sensing platforms are presented. Finally, the discussions on both biosensor techniques as well as comparison of both SPR sensing techniques are made. (© 2012 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

Url:
DOI: 10.1002/jbio.201200015


Affiliations:


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